Bryn Marie Reimer

I’m Bryn Marie Reimer, a computational/data scientist and current PhD candidate at UMass Amherst. I work both on applied and theoretical projects, building predictive models with small molecule, genomic, and proteomic data and using data science and domain knowledge to improve understanding of the inner mechanisms of these models. I am also passionate about teaching and mentoring students.

As of Fall 2026, I am also actively on the academic job market search for a tenure-track position, especially at a small liberal arts college.

My CV has more information, including contact details.

Other relevant links:

• Bryn Marie Reimer, Anna G. Green. A frameshift mutation in the methyltransferase rlmN is associated with increased linezolid resistance in Mycobacterium tuberculosis. Computational and Structural Biotechnology Journal 2026 web PDF
• Deborah Castelletti, …, Bryn Marie Reimer, …, Wolfgang Jahnke. Fragment-based discovery enables direct targeting of the melanoma oncogene MITF. Nature Communications 2025 web PDF
• Bryn Marie Reimer, …, Viktor Hornak. CovCysPredictor: Predicting selective covalently modifiable cysteines using protein structure and interpretable machine learning. Journal of Chemical Information and Modeling 2025 web PDF
• ‡Xiaojian Shi, ‡Bryn Reinstadler, …, Hongying Shen. Combinatorial GxGxE CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport. Nature Communications 2022 web PDF
• Rohit Sharma, Bryn Reinstadler, …, Vamsi K Mootha. Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity. The Journal of Clinical Investigation 2021 web PDF

• [CS-relevant] Dynamo: Dynamo is a website built by Bryn Reimer, Bao Nguyen, and Cullen Anderson to help students understand dynamic programming through a combination of text, worked examples, and self-quizzes. Read more...
• [other] Calling It Round: Calling It Round is a web-based publication developed by Bryn Reimer that aims to explain a complex, niche topic (conducting English change [bell] ringing bands) to beginning change ringers to improve equity and access to the highest levels of achievement in bell ringing. Read more...